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Biopharmaceuticals and medicine

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Filtration processes are widely used in pharmaceutical and biotechnological production.

 

 

The company "Technofilter" offers a wide range of membrane and other separation technologies used at different stages of production of drugs. Industrial filters and equipment SPE "Technofilter" is widely used by manufacturers of medicines in Russia and abroad. We produce a wide range of membranes, cartridge and capsule filter elements, filter holders and filtration systems in the pharmaceutical industry.

 

Our filtration products are used for preliminary, clarifying and sterilizing filtration

 

Solutions for parenteral nutrition large (LVP) and small (SVP) volumes

 

protein preparations of blood

 

culture and bacterial media

 

blood serum

 

ophthalmic and alcohol solutions

 

biological fluids

 

vitamins and galenic preparations

 

water for pharmaceutical use (water for injection, washing machines, autoclaves, pyrogen-free water, filtration at points of consumption, circulating water, water for rinsing ampoules and vials)

 

preparation of buffer solutions

 

removal of bacteria and mycoplasma

 

removal of viruses and pyrogens from aqueous solutions, water for injection

 

removal of lipids and colloids from biologics, protein solutions, serums

 

decolorization of solutions of pharmaceutical substances

 

clarification of carbon-containing solutions

 

clarification and maintenance of galenic preparations, extracts, etc.

 

removal of fine particles of activated carbon particles

 

Sterile filtration of process air, nitrogen and other gases for feeding into the filling zone

 

purification of steam for autoclaves and sterilization of equipment

 

sterile ventilation of tanks and fermenters - "breathing" filters

 

protection of water treatment systems, chromatography columns

 

other applications

 

 

Industrial filtration

 

 

 

Sterilizing filtration

 

Technofilter produces a wide range of sterilizing filters in the form of standard filter cartridges and HYPERLINK  capsules for liquids and gases with various membrane materials:

 

- Polyamide (Nylon) is characterized by high productivity and wide chemical compatibility as a membrane material for HYPERLINK filters EPMK - / 020

 

- Polyamide (Nylon) with Z-potential as membrane material for HYPERLINK filters EPMK + / -020 for sterilizing filtration of liquid media with control of pyrogenicity.

 

- polyethersulfone has wide chemical compatibility (pH = 1-14), high heat resistance and throughput, low sorption with respect to proteins, enzymes and proteins. The pronounced asymmetric structure and the increased total porosity of the membrane ensure reliable removal of microorganisms at high flow rates using HYPERLINK filter elements EPM-PS-020

 

- polytetrafluoroethylene - hydrophobic membrane, specially developed for sterilizing filtration of air, compressed gases and hydrophobic liquids in HYPERLINK filter elements EPM.F4-020

 

- polypropylene - a special hydrophobic membrane made of PP, developed for the filtration of gas media and non-aqueous solutions of EPMP-020 grade.

 

 

Prefiltration and clarification

 


Prefilters "Technofilter" have a different design and materials:

 

Membrane:

EPMK is a prefilter with a polyamide membrane

 

EPMK - prefilter with polyamide membrane with a layer of fiberglass

 

EPMMS - a prefilter with a membrane of polyethersulfone

 

EPM.FG is a prefilter with a membrane of hydrophilized fluoroplastic (PVDF)

 

EPMF is a prefilter with a membrane of hydrophobic fluoroplastic (PTFE + PVDF)

 

Corrugated:

 

EPVg.P is a corrugated universal polypropylene filter of increased density

 

EPVS is a corrugated filter of 100% microglass fiber

 

EPVC is a corrugated filter made of glass, cellulose and polypropylene microfibers

 

EPNS.P - corrugated all-metal filter made of stainless steel for the filtration of steam, corrosive liquids and gases

 

EPSC - corrugated stainless steel filter for the processes of preliminary filtration of high-viscosity media and highly contaminated solutions

 

 

 

Filters integrity monitoring

 

The integrity of the filters and biological safety is controlled through the determination of diffusion, bubble point and pressure drop, and for hydrophobic materials - a water intrusion test. The results of these tests are correlated with the Bacteria Challenge Test.

 

 

 

In this section, we confine ourselves to the main technological processes, where our filtration equipment is successfully used. The choice of equipment, as a rule, is multifaceted, and depends on the specific conditions of the production process.

 The products for each type of product are given the main recommendations for use. Since each process is unique, these recommendations should be taken into account as a starting point. We ask you to consult with technical experts of "Technofilter" on application for making a decision on the choice of equipment for a particular process.


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