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Industrial filters for water. Filtration of water for pharmaceutical use. Filtration of water for injection. Filters for water purification

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Filtration of water for pharmaceutical use. Filtration of water for injection. Filters for water purification


Water for pharmaceutical use is widely used in the manufacture of medicines and feeds the general stages of processes, such as washing machines, autoclaves, systems for obtaining water for injection, circulating water. In the central distribution system, filtering through cartridge microfilters is only one of several processing steps. Other steps (ion exchange, filtration through a layer of coal, precipitation) can strongly contaminate the water with a fine fraction of resin and coal and require additional purification through cartridge microfilters.



Process Requirements


Prefilters should effectively remove most particles and colloidal contaminants, should be distinguished by their high mud capacity, natural hydrophilicity, excellent heat resistance, high flow rates and a stable high resource over time.


Finishing membrane filters should effectively remove microorganisms and bacterial endotoxins (pyrogens), subject to integrity testing. The coordinated combination of the prefilter and the final filter provides a high flow rate and stability of the working resource.


Purposes of filtration




remove colloids and particles to extend the life of the final filters.

Finishing filtration


remove particles, microorganisms and endotoxins.




Recommendations for filters Technofilter


For final (sterilizing) filtration, when no removal of endotoxins is required, or to lower the bioburden before a charged filter,  EPMK- 045/020 based on a polyamide membrane. If the filter is used at elevated operating temperatures (over 600 ° C), we recommend a  EPM-PS-045/020 based on a high-performance heat-resistant membrane of polyether sulfone.


For the removal of bacterial endotoxins, we propose filtering elements based on a positively charged membrane of the brand EPMK + -045 / 020. The charged hydrophilic filtering element EPM.K + is specifically designed to remove bacterial endotoxins and viruses from aqueous pharmaceutical grade systems. Endotoxins can easily pass through a conventional uncharged sterilizing filter with a pore size of 0.2 μm, because their size is much smaller than the pore size of the membrane. However, due to a positive charge, the EPM.K + membrane is capable of retaining negatively charged endotoxins. The results of the membrane study see here.


For qualitative preliminary and final depth filtration we recommend cartridge filters of the  EPVg.P. The filter elements of this series are capable of providing high flow rates, excellent mechanical and thermal stability, can operate at a constant temperature of 900C, have low initial resistance, high retention of microparticles, do not release fibers into the filtrate, are manufactured according to ISO 9001: 2000. In most cases, cartridge filters EPVg.P with a rating of 1-5 microns are recommended.



For rough preliminary filtration of water on ampoules (from glass fragments and other large mechanical inclusions), we recommend the repeatedly regenerated  EPNS.


For sterilizing air filtration ("breathing" filters) we recommend membrane filter elements from polytetrafluoroethylene brand EPM.F4 or hydrophobic fluoroplastic F42 brand EPMF with 0.2 μm pore size.


For the organization of the filtration process, we offer enclosure equipment - medical  filter holders of the DS series from high-quality stainless steel AISI 316L or AISI 304 (12Х18Н10Т) for different number and height of filter elements and filtration plants based on them.


For the final choice of the scheme for the filtration process, please contact the specialists of  Technofilter.

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